Clinical Bioinformatician Sr
Job ID:
R145599
Shift:
1st
Full/Part Time:
Full_time
Pay Range:
$40.30 – $60.45
Location:
Rosemont, IL – 5400 Pearl St
Rosemont, IL 60018
Benefits Eligible:
Yes
Hours Per Week:
40
Our Commitment to You:
Advocate Health offers a comprehensive suite of Total Rewards: benefits and well-being programs, competitive compensation, generous retirement offerings, programs that invest in your career development and so much more – so you can live fully at and away from work, including:
Compensation
- Base compensation within the position’s pay range based on factors such as qualifications, skills, relevant experience, and/or training
- Premium pay such as shift, on call, and more based on a teammate’s job
- Incentive pay for select positions
- Opportunity for annual increases based on performance
Benefits and more
- Paid Time Off programs
- Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability
- Flexible Spending Accounts for eligible health care and dependent care expenses
- Family benefits such as adoption assistance and paid parental leave
- Defined contribution retirement plans with employer match and other financial wellness programs
- Educational Assistance Program
Schedule Details/Additional Information:
M-F 9AM-5PM – Either remote or hybrid options
MAJOR RESPONSIBILITIES
- Lead project management efforts, ensuring timely completion of goals and projects in alignment with strategic plans, and identify necessary resources for successful delivery.
- Conduct regular audits of bioinformatics processes to identify areas for improvement and ensure compliance with best practices and regulatory requirements.
- Implement and manage bioinformatics methodologies and pipelines for somatic and germline targeted genes sequencing, exhibiting good code and development practice.
- Analyze and interpret NGS data from various sequencing platforms (e.g., Illumina, Ion Torrent) for clinical applications such as hereditary disease diagnostics, cancer genomics, and solid tumor mutation detection.
- Hands-on design, develop, and optimize bioinformatics pipelines for tasks like variant calling, copy number variation (CNV) detection, structural variant analysis, and gene expression profiling.
- Work closely with clinical laboratory staff, pathologists, directors, and researchers to translate bioinformatics analyses into actionable clinical insights. Communicate complex bioinformatics concepts and results to non-technical stakeholders in a clear and effective manner.
- Assess data analysis workflows to identify opportunities for automation of analysis, reporting, and quality control (QC). Implement improvements in collaboration with laboratory leadership.
- Ensure all bioinformatics workflows and analyses comply with clinical laboratory regulations and standards (e.g., CLIA, CAP). Lead the validation and verification of bioinformatic systems, including modifications, upgrades, and other changes; develop and maintain documentation for bioinformatics processes.
- Develop and implement bioinformatics policies and practices that adhere to CLIA, CAP, CDC, OSHA, AABB, and FDA guidelines. Oversee CAP bioinformatics surveys and ensure compliance with CAP inspections. Monitor regulatory changes and update policies accordingly.
- Ensure the implementation of effective quality assurance and quality control programs, integrating with related committees and processes to maintain high standards.
MINIMUM EDUCATION AND EXPERIENCE REQUIRED
- Education Required:
- Ph.D. in Bioinformatics, Statistics, Computer Science, data science or a related field and 3+ years of bioinformatics experience, OR
- Master’s degree with 5+ years of experience, OR
- Bachelor’s degree with 8+ years of experience.
- Experience Required:
- Experience with Linux-based or cloud computing environments.
- Proficiency in Python, R for developing somatic and germline analysis pipelines, with experience managing the codebase using Git.
- Proven experience in NGS data analysis, variant detection, and annotation.
KNOLWEDGE, SKILLS AND ABILITIES REQUIRED
- Familiar with the basic of genomics, genetics or molecular and cell biology.
- Proficiency in Python, R, Bash, or similar programming/scripting languages.
- Experience with high-performance computing (HPC) and cloud platforms is preferred.
- Ability to write custom code for constructing analysis pipelines and manipulating sequence data.
- Familiarity with cancer genomics, liquid biopsy, or hereditary disease testing preferred.
- Experience with machine learning applications in bioinformatics.
- Demonstrated organizational ability, attention to detail, and accuracy.
- Effective written and verbal communication skills and ability to build rapport and relate to all people.
- Ability to work in a fast-paced environment and to handle multiple tasks simultaneously.
- Excel with working independently, troubleshooting problems, and providing solutions.
- Ability to speak effectively and present material to be understood by a diverse group of individuals.
- Maintains patient confidentiality in and out of the workplace.
PHYSICAL REQUIREMENTS AND WORKING CONDITIONS
- Operates all equipment necessary to successfully perform all job responsibilities.
- Must have fine motor skills and manual dexterity.
- Frequently lifts to 10 lbs. Occasionally lifts to 50 lbs.
- Must be able to sit, stand, walk, and bend much of the workday.
- May be exposed to mechanical, electrical, chemical, radioactive and/or infectious agents.
- Will be exposed to human blood, tissue, and body fluids.
- Must wear appropriate Personal Protective Equipment (PPE) as needed.
This job description indicates the general nature and level of work expected of the incumbent. It is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities required of the incumbent. Incumbent may be required to perform other related duties.
Advocate Health Care is the largest health system in Illinois and a national leader in clinical innovation, health outcomes, consumer experience and value-based care. One of the state’s largest private employers, the system serves patients across 11 hospital locations, including two children’s campuses, and more than 250 sites of care. Advocate Health Care, in addition to Aurora Health Care in Wisconsin and Atrium Health in the Carolinas, Georgia and Alabama, is now a part of Advocate Health, the third-largest nonprofit, integrated health system in the United States. Committed to providing equitable care for all, Advocate Health provides nearly $5 billion in annual community benefits.
